{
  "product_id": "profiler_16442",
  "product_name": "PROFILER®",
  "registration_number": "16442",
  "manufacturer": "Bayer CropScience S.r.l.",
  "active_ingredients": [
    "fluopicolide",
    "fosetyl-aluminium"
  ],
  "active_ingredient_concentrations": [
    "44.4 g/kg",
    "666.7 g/kg"
  ],
  "frac_groups": [
    "43",
    "33"
  ],
  "organic_certified": false,
  "target_crops": [
    "grapevine"
  ],
  "target_diseases": [
    "downy mildew"
  ],
  "action_type": [
    "fungicide"
  ],
  "systemicity": "mixed",
  "preventive_action": true,
  "curative_action": false,
  "eradicant_action": false,
  "recommended_disease_pressure": "Use shorter interval and higher dose under environmental conditions favorable to pathogen development.",
  "reentry_interval_hours": null,
  "min_spray_volume": 1000.0,
  "max_spray_volume": 1000.0,
  "phenology_constraints": "",
  "weather_constraints": "Apply in the absence of wind.",
  "rainfastness": "",
  "temperature_constraints": "",
  "humidity_constraints": "",
  "mixing_incompatibilities": "May have compatibility issues when mixed with formulations containing copper, some biostimulants, and foliar fertilizers containing nitrogen (nitric and ammoniacal). Do not mix with oil-based formulations. It is advisable to carry out preliminary tests to verify compatibility. If mixed with other formulations, the longest pre-harvest interval must be respected.",
  "phytotoxicity_constraints": "",
  "environmental_restrictions": "Toxic to aquatic life with long lasting effects. May cause long-term and widespread contamination of water resources. To protect groundwater, do not apply on soils containing more than 80% sand. Do not contaminate water with the product or its container. Do not clean application equipment near surface water. Avoid contamination via drainage systems from farms and roads.",
  "buffer_zone_requirements": "",
  "resistance_management_summary": "It is advisable to alternate this product with fungicides having a different mechanism of action. On wine grapes, if alternating with fluopyram-based formulations, do not exceed 2 total treatments per year. If tank-mixing with fluopyram-based products, apply only once per year. Do not apply fluopicolide-based products if 2 applications of fluopyram-based products are made per year.",
  "application_recommendations": "Pour the product directly into the sprayer tank half-filled with water, then fill with the remaining water and keep agitated. For low or ultra-low volume equipment, the product concentration must be increased to ensure the same dosage per hectare.",
  "safety_notes": "Causes serious eye irritation. Suspected of damaging the unborn child. Wear suitable gloves during mixing/loading and application. Wait until vegetation is completely dry before re-entering the treated area.",
  "retrieval_summary": "PROFILER® is a fungicide for the preventive control of downy mildew (Plasmopara viticola) on grapevine. It contains fluopicolide (FRAC 43) and fosetyl-aluminium (FRAC 33), providing mixed systemic and translaminar activity. The product is applied from pre-flowering to fruit set, with a maximum of two applications per season at a 10-14 day interval. Key constraints include a 28-day pre-harvest interval, specific resistance management rules regarding alternation with fluopyram, and incompatibility with copper, certain foliar fertilizers, and oil-based formulations. It is toxic to aquatic life and has restrictions on use in sandy soils to protect groundwater.",
  "uses": [
    {
      "crop": "grapevine",
      "disease": "downy mildew",
      "setting": "",
      "dose_min": 2.25,
      "dose_max": 3.0,
      "dose_unit": "kg/ha",
      "concentration_min": 225.0,
      "concentration_max": 300.0,
      "concentration_unit": "g/hl",
      "treatment_interval_min_days": 10,
      "treatment_interval_max_days": 14,
      "max_treatments_per_season": 2,
      "pre_harvest_interval_days": 28,
      "spray_volume_min": 1000.0,
      "spray_volume_max": 1000.0,
      "growth_stage_start": "pre-flowering",
      "growth_stage_end": "fruit set"
    }
  ],
  "low_confidence_fields": [
    "reentry_interval_hours"
  ],
  "extraction_notes": "The label specifies re-entry is permitted once vegetation is dry, rather than a fixed number of hours, so reentry_interval_hours is set to null.",
  "reviewed": false,
  "source_label_version": "09/06/2023",
  "source_file": "PROFILER.pdf",
  "last_update": "2024-06-21"
}